Senior Program Officer, Software & AI

The Foundation

We are the largestnonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees should reflect the rich diversity of the global populations we aim to serve. We provide an exceptional benefits package to employees and their families which include comprehensive medical, dental, and vision coverage with no premiums, generous paid time off, paid family leave, foundation-paid retirement contribution, regional holidays, and opportunities to engage in several employee communities. As a workplace, we’re committed to creating an environment for you to thrive both personally and professionally.

The Team

Your Role

The Senior Program Officer (SPO), Software & AI, will serve as a technical and strategic lead for software, digital health, and AI-enabled products across the MNCNH portfolio. The role will help translate high-priority health use cases into products and platforms that are technically sound, user-centered, interoperable, and deployable in low-resource settings. The portfolio may include clinical decision support, risk-stratification tools, AI-enabled applications, digital workflows, software that connects to medical devices, and other data- and software-driven approaches that improve individual-level care and health-system performance. A flagship priority for this role is accelerating risk-stratification software layered on top of the foundation's AI-enabled hardware investments — spanning antenatal ultrasound, intrapartum monitoring, and postpartum/neonatal care — turning imaging and physiologic signal data into clinically actionable outputs. The SPO will hold grantmaking responsibility for a defined portfolio of investments and work closely with MNCNH technical leads, country teams, and partners to move promising concepts from prototype through validation, productization, integration, and scale.

While primarily anchored in MNCNH, this role will also serve as a shared technical resource for selected software and AI use cases across the broader Women’s Health portfolio. Success will require strong product and software-development judgment, fluency in rapidly evolving AI technologies — equally at ease with classical/deterministic modeling and generative AI methods, and able to judge which approach a given clinical use case actually calls for, and the ability to connect technical choices to real-world implementation constraints. The SPO will work across internal teams and with grantees, technology companies, software developers, researchers, implementing partners, governments, and other stakeholders to ensure that solutions are designed for local workflows, data environments, connectivity constraints, and sustainable country ownership.

What You’ll Do

• Lead and manage a portfolio of grants, contracts, and other investments focused on software, digital health, and AI-enabled products, from sourcing and diligence through structuring, execution, monitoring, and reporting.

• Translate MNCNH and selected broader Women’s Health priorities into clear software and AI product roadmaps, identifying the highest-value use cases, portfolio gaps, technical dependencies, and build-versus-partner decisions.

• Provide technical leadership across the software product lifecycle, including product requirements, user-centered design, architecture, software development, testing, deployment, maintenance, and product iteration.

• Guide the development and productization of AI-enabled tools, including clinical decision support, risk stratification, workflow automation, multimodal and generative AI applications, and software that connects to medical devices or other digital platforms.

• Define how imaging (e.g., ultrasound) and physiologic signal data (e.g., intrapartum and neonatal monitoring) pools are structured, labeled, and converted into validated, productized software outputs, partnering with the foundation's data team on shared standards and infrastructure.

• Assess technical architecture and integration requirements, including APIs, interoperability, data flows, identity and access, cloud/edge/local deployment, offline and low-bandwidth operation, and integration with existing health information systems and digital public infrastructure.

• Partner with grantees, developers, researchers, country stakeholders, and implementation partners, working closely with other Program Officers across the hardware and clinical portfolio and the foundation's data team, to ensure products are designed around frontline workflows and can move from prototype or pilot to reliable, maintainable, scalable use, including at regional deployment and pilot sites.

• Apply strong judgment on responsible AI, data governance, privacy, security, clinical safety, model performance, and human oversight, and establish clear evidence and decision criteria for when products are ready to advance, scale, pause, or stop.

• Stay closely connected to the evolving software and AI ecosystem, including emerging models, platforms, vendors, and technical approaches, and translate relevant developments into practical implications for the portfolio.

• Contribute to budgeting, risk management, and sequencing of investments, with clear milestones, decision points, technical deliverables, and outcomes that support effective stewardship of foundation resources.

• Track and communicate portfolio progress and translate complex technical, product, implementation, and market evidence into clear recommendations for team and foundation leadership.

• Foster coordination across MNCNH, Women’s Health, country teams, and relevant foundation-wide digital and AI teams so that use cases build on shared capabilities rather than creating duplicative or disconnected solutions.

• Build and sustain an external ecosystem of software developers, AI companies, researchers, digital-health experts, implementers, governments, and other partners needed to advance affordable and scalable solutions for low- and middle-income countries.

• Represent the Foundation externally, including at technical and industry meetings, partner convenings, advisory groups, and engagements with governments, technology companies, and implementing organizations.

Your Experience

• Advanced degree in computer science, software engineering, data science, biomedical informatics, engineering, medicine, public health, or another relevant technical or clinical discipline.

• Minimum 10 years of relevant experience developing, launching, and scaling software, digital-health, data, or AI-enabled products; experience with health or other high-stakes applications is strongly preferred.

• Deep technical and product knowledge in several of the following areas: software architecture, APIs and interoperability, mobile or web applications, cloud and edge computing, data platforms, artificial intelligence/machine learning, generative AI, clinical decision support, risk stratification, or software as a medical device.

• Demonstrated fluency in both classical/deterministic modeling (e.g., clinical risk scores, statistical and rules-based methods) and generative AI approaches, with sound judgment about which fits a given clinical use case. Experience working with imaging (e.g., ultrasound) and/or physiologic signal data (e.g., intrapartum or neonatal monitoring), and experience in a regulated medical device (SaMD) context, is strongly preferred.

• Demonstrated ability to translate user and program needs into product requirements and technical roadmaps, and to work effectively with engineering teams from early prototype through deployment and iteration.

• Strong understanding of responsible AI, data governance, privacy, security, model evaluation, clinical safety, and the evidence needed to support adoption and scale of software-enabled health products.

• Experience designing or deploying products in constrained environments, including low-connectivity settings, fragmented data ecosystems, limited device access, or complex government and health-system workflows.

• Demonstrated ability to set strategy, make portfolio and investment decisions, and manage complex programs with clear milestones, budgets, risk mitigation, and outcomes.

• Strong external network and demonstrated ability to stay current in a rapidly evolving technology landscape and distinguish durable capabilities from short-lived trends or vendor-specific solutions.

• Experience working across traditional disciplinary boundaries and with senior leaders, software engineers, data scientists, clinicians, researchers, governments, technology companies, and implementation partners.

• Excellent written, verbal, and presentation skills, with the ability to communicate complex technical concepts clearly to diverse audiences and build alignment across a highly matrixed environment.

• Proven ability to build and manage multi-stakeholder partnerships across technology, academia, industry, governments, and implementing organizations.

• Global health experience is strongly preferred; experience developing and deploying software or AI-enabled products in low- and middle-income countries and/or women’s, maternal, newborn, and child health is ideal.

• Ability to travel domestically and internationally up to approximately 30% of the time.

The salary range for this role is $212,800 to $329,800 USD.  We recognize high-wage market differences in Seattle and Washington D.C., where our offices are located.  The range for this role in these locations is $234,000 to $362,800 USD.  As a mission-driven organization, we strive to balance competitive pay with our mission.  New hires salaries are typically between the range minimum and the salary range midpoint. Actual placement in the range will depend on a candidate’s job-related skills, experience, and expertise, as evaluated during the interview process.

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Hiring Requirements

As part of our standard hiring process for new employees, employment will be contingent upon successful completion of a background check.

Candidate Accommodations

We’re committed to providing an inclusive and accessible hiring experience for all candidates. If you have a disability or medical condition and need an accommodation at any stage of the application or interview process—such as an ASL interpreter, alternative interview format, or physical accessibility support—we’re happy to help. Please contactHR@gatesfoundation.org with the position number and a brief description of your accommodation needs. Requests will be handled confidentially.

Inclusion Statement

We are dedicated to the belief that all lives have equal value. We strive for a global and cultural workplace that supports ever greater diversity, equity, and inclusion — of voices, ideas, and approaches — and we support this diversity through all our employment practices.

All applicants and employees who are drawn to serve our mission will enjoy equality of opportunity and fair treatment without regard to race, color, age, religion, pregnancy, sex, sexual orientation, disability, gender identity, gender expression, national origin, genetic information, veteran status, marital status, and prior protected activity.