Research Associate I

Assay Development & Bioinformatics

Position Summary

The Research Associate I supports cross-functional molecular diagnostics research projects through the execution of laboratory experiments, generation of high-quality data, and maintenance of laboratory operations. Working closely with Assay Development and Bioinformatics teams, this individual performs molecular biology workflows, supports high-throughput screening activities, organizes experimental data, and contributes to data-driven assay development efforts.

The position serves as a bridge between laboratory experimentation and computational analysis, ensuring the generation and organization of high-quality data to support assay design and optimization activities. This position is ideal for an early-career scientist interested in molecular diagnostics, assay development, laboratory automation, and data-centric research.

Key Responsibilities

• Perform molecular biology and assay development experiments following established protocols and study plans.
• Prepare reagents, controls, oligonucleotides, standards, and biological samples for assay development activities.
• Execute PCR, qPCR, RT-PCR, and other nucleic acid-based workflows using laboratory instrumentation and automated systems.
• Support high-throughput screening studies through plate preparation, sample processing, and operation of laboratory automation platforms.
• Collect, organize, document, and summarize experimental data in laboratory notebooks and electronic data management systems.
• Assist with data compilation, quality checks, and preparation of datasets and associated metadata for downstream analysis.
• Communicate experimental results, observations, and technical issues to project team members and supervisors.
• Operate, maintain, and troubleshoot laboratory equipment and instrumentation as needed.
• Manage laboratory inventory and support routine laboratory operations.
• Follow established SOPs, laboratory safety requirements, and quality standards.
• Collaborate effectively with scientists and bioinformaticians to support project goals and timelines.

Qualifications

Required

• B.S. or B.A. in Molecular Biology, Biology, Biochemistry, Biotechnology, Chemistry, Genetics, or a related life science discipline.
• 0-2 years of laboratory experience in academic research, biotechnology, diagnostics, or related fields.
• Basic understanding of molecular biology techniques, including PCR and qPCR.
• Proficiency with Microsoft Office applications, particularly Excel, Word and PPT.
• Strong organizational skills and attention to detail.

Preferred

• Experience with molecular diagnostic assays.
• Experience with automated liquid handling systems or other laboratory automation platforms.
• Familiarity with high-throughput screening workflows.
• Exposure to biological data analysis, data visualization, or bioinformatics concepts.
• Experience working in a regulated laboratory environment.

Intake Notes:

Role Overview

• Job Title: Research Associate I
• Department: Assay Development & Bioinformatics
• Number of Openings: 2
• Location: 10210 Genetic Center Dr., San Diego, CA 92121
• Work Model: Onsite
• Duration: 6 Months
• Extension Possible: Yes
• Conversion Possible: Yes
• Target Start Date: ASAP

Business Need

• Support AI/ML-assisted oligonucleotide design initiative.
• Generate high-quality experimental data to support molecular assay development.
• Partner closely with Assay Development and Bioinformatics teams.

Top Required Skills

1. Molecular biology techniques (PCR, qPCR, ddPCR, nucleic acid extraction)
2. Experimental troubleshooting and data interpretation
3. Collaboration within cross-functional scientific teams

Must-Have Qualifications

• BS/BA in Molecular Biology, Biotechnology, Biochemistry, Genetics, or related life science field
• Hands-on PCR/qPCR experience
• Molecular biology laboratory experience
• Experience analyzing and interpreting experimental data
• Strong documentation and organizational skills
• Statistical analysis using JMP or similar software

Preferred Qualifications

• Molecular diagnostics experience
• Laboratory automation/liquid handling systems
• High-throughput screening experience
• Python, R, JMP, or bioinformatics exposure
• Oligonucleotide design experience

Candidate Knockouts

• No qPCR experience
• No molecular biology lab experience
• Cannot explain troubleshooting examples
• No data analysis/interpretation experience

Team & Environment

• Small collaborative team (5-6 scientists and research associates)
• Reports to Kati Hokynar
• Works closely with Meghan Altman and Bioinformatics team members